Polynucleotide (PDRN) Treatment in Dubai: Plinest and Rejuran

What polynucleotides are, in plain terms

PDRN stands for polydeoxyribonucleotides: short fragments of DNA used in aesthetic medicine as injectable skin boosters. Patients search for them as polynucleotides, PDRN or, because the DNA is commonly taken from fish such as salmon, “salmon DNA injections”. They are a different material from hyaluronic acid. A hyaluronic acid booster binds water. A polynucleotide preparation is chosen to work on skin quality by another route.

Both kinds are injected into the skin to change its quality, not to add volume or reshape the face. A line or a hollow that needs filling is a filler question. Our page on skin boosters and fillers explains the difference.

For the science behind PDRN, including where it comes from and how it is studied, read the clinic’s PDRN evidence review.

Plinest and Rejuran at MED YU MED

Polynucleotides are booked through our biorevitalization service, alongside the hyaluronic acid boosters. The doctor selects the product from your skin concern, the treatment area and the result you want. The price list carries these polynucleotide products:

• Plinest (2 ml)
• Plinest Eye (2 ml, PDRN)
• Rejuran S (PDRN)
• Rejuran i (PDRN)
• Rejuran Healer (PDRN)

We do not match each product to a skin problem on this page, because that is a clinical decision made after examination, not a menu choice. Ask the doctor why a product is proposed for you.

Treatment can be done on the face, the under-eye area, the neck, the décolleté, the hands and selected body areas, each after the doctor’s assessment. The under-eye area carries a higher risk of swelling and of vascular complications, so it is treated only after assessment and is not suitable for everyone.

Who polynucleotide treatment may suit

Skin boosters may suit dehydrated, dull skin with fine lines, reduced elasticity, uneven texture or early signs of photoageing. The doctor decides from your skin condition, not from a fixed age. The doctor also checks whether a combination with lasers, peels or PRP makes sense and how to space the visits.

Polynucleotides are not a wrinkle filler or a contouring treatment. If your main concern is volume, a deep fold or facial shape, the plan will look different, and sometimes boosters and fillers are used together: boosters for skin quality, fillers for structure.

How a visit works

Polynucleotides go through the same service as our other skin boosters, so the visit follows the same four steps.

1. Consultation. The doctor checks skin hydration, elasticity, sensitivity, inflammation, pigmentation risk, previous procedures, allergies and contraindications. Then the doctor selects the product, the injection technique and the number of sessions.
2. Preparation. The skin is cleansed and a topical numbing cream is applied. The doctor plans the injection points.
3. Injection. The doctor places small amounts of the product into the skin with a very fine needle. A skin booster session usually takes 20 to 30 minutes, depending on the area and the product.
4. Aftercare. The doctor explains what to expect and what to avoid. Keep the skin clean and use SPF.

The doctor sets the number and spacing of sessions, and repeated treatments are typical. We do not quote a fixed number of sessions or a fixed interval here, because that depends on your skin and the product, and the doctor adjusts the plan as your skin responds.

After the session: what to expect

For skin boosters at our clinic, small raised bumps at the injection points usually flatten within 24 to 72 hours and can stay visible for up to a week. Mild redness and the odd pinprick bruise are possible. Bruising around the eyes lasts longer. Avoid make-up, heat, saunas, heavy exercise and direct sun for the rest of the day. These timings describe our skin booster service as a whole. With polynucleotides they may differ, and the doctor tells you what to expect with your product.

Skin quality changes gradually. We do not promise a specific result or a timeline. Results vary from person to person, and the doctor reviews progress with you through the course.

Polynucleotide prices in Dubai

Each product is sold as a single session, a course of three or a course of 4+1. The doctor recommends how many sessions you need after examining your skin, so the table shows the price options, not a treatment plan.

Single-session prices from the MED YU MED price list; course prices from the biorevitalization page. Both checked 30 September 2026. The final plan and cost are confirmed at the consultation.

What the evidence shows, and what it does not

We do not repeat the research here. The clinic’s evidence review covers what PDRN is, where it is used and what has been studied. Read it before you decide.

The evidence base for polynucleotides in aesthetic use is limited, and we give you no figures for how much any product improves skin. We do not quote a number of sessions or an interval for Plinest or Rejuran on this page; the doctor sets them for you. We describe polynucleotides as a way to support skin quality. We do not describe them as a way to change your features.

Who should wait, and who needs a doctor’s decision first

This list is not exhaustive. Medicines, previous treatments and your medical history can change the plan. A licensed doctor decides whether treatment is suitable at an in-person assessment.

Risks and side effects

Expected effects are small raised bumps at the injection points, mild redness and occasional bruising. Less common effects are infection at an injection point, an allergic reaction and prolonged swelling. Rarely, a product is injected into a blood vessel, which can damage the skin and, very rarely, affect vision. The risk is highest around the eyes. DHA-licensed doctors perform the injections and explain these risks to you before treatment.